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Azelaic acid is a dicarboxylic acid used to treat mild to moderate acne by decreasing inflammation and redness. It is also an antioxidant that can neutralize free radicals. Azelaic acid is available in topical creams and gels, and can be used once or twice a day. It kills bacteria on the skin that causes acne and assists with cellular turnover as an exfoliant. Azelaic acid is often combined with oral antibiotics or hormonal therapy for acne treatment. It is safe to use every day and is a good option for those with sensitive or dry skin. However, if you have oily skin, salicylic acid may be a better choice. Retinol and azelaic acid have different roles, with retinol assisting in cell renewal and azelaic acid in bacteria and inflammation reduction.