Welcome to the tag category page for Signs and symptoms!
Hypermobility refers to the ability of joints to move beyond the normal range of motion. It can cause pain and discomfort in individuals who have extremely flexible joints. Joint hypermobility syndrome (JHS) is a genetic condition characterized by extreme flexibility along with symptoms such as pain. About 30% of the population is affected by hypermobility, and around 10% of them experience symptoms. Hypermobility spectrum disorders (HSD) are connective tissue disorders that cause joint hypermobility, instability, injury, and pain. Diagnosis of hypermobility syndrome is typically done using the Beighton score and Brighton criteria. Treatment usually focuses on improving muscle strength and fitness to protect the joints. It is advised not to train to fatigue in order to prevent further instability. Overall, hypermobility can have various systemic symptoms and affect daily functioning.
Pancreatic elastase is an enzyme produced by the pancreas that aids in the digestion of proteins. It is an important marker in assessing the function of the pancreas and diagnosing exocrine pancreatic insufficiency (EPI), a condition where the pancreas does not produce enough digestive enzymes. The stool elastase test is commonly used to measure pancreatic elastase levels. This non-invasive test helps determine if the pancreas is functioning properly, with lower levels indicating pancreatic exocrine insufficiency. EPI can cause symptoms such as belly pain and digestive problems and can lead to malnutrition if left untreated. Treatment for EPI typically involves pancreatic enzyme replacement therapy (PERT), which helps improve digestion and nutrient absorption. Prompt diagnosis and treatment of EPI can alleviate symptoms and prevent complications associated with malnutrition.
Elastase is an enzyme classified as a serine protease that is involved in breaking down proteins, particularly elastin found in connective tissue. It preferentially cleaves at the C-terminus of specific amino acids and has the ability to induce the disintegration of the axoneme in the presence of ATP. Elastase is also expressed in neutrophils and plays a crucial role in immune responses. Overall, elastase is an essential enzyme with specific functions in protein degradation and various biological processes.
The ALP test, or alkaline phosphatase test, is a medical test that measures the amount of alkaline phosphatase (ALP) in the blood. ALP is an enzyme that is found throughout the body and is commonly used to diagnose liver damage or bone disorders. The ALP test can be used for screening, diagnosis, and monitoring of various health conditions. Low levels of ALP can indicate a deficiency in zinc and magnesium, as well as a rare genetic disease called hypophosphatasia. High levels of ALP in the blood may indicate liver disease or certain bone disorders. The ALP test is often used to screen for or help diagnose diseases of the liver or bones. It can also be used to monitor other health conditions.