Welcome to the tag category page for Rheumatoid arthritis!
Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used to treat conditions such as osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps in familial adenomatous polyposis. It works by reducing hormones that cause inflammation and pain in the body. However, NSAIDs, including celecoxib, may cause ulcers, bleeding, or holes in the stomach or intestine, and may raise the risk of having a heart attack or stroke, especially in people who already have heart disease. Celecoxib has been compared to ibuprofen and found to be similarly effective for many types of pain. It is not a narcotic and does not work as a muscle relaxer. The brand name for celecoxib is Celebrex. Merck withdrew the drug Vioxx, which is similar to Celebrex, from the market in 2004 after a clinical trial revealed it increased the risk of heart attacks. However, the question of whether Celecoxib also causes heart attacks remains uncertain.
Etoricoxib is a selective COX-2 inhibitor used to relieve pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and gout. It is approved for use in multiple countries worldwide but was not approved by the FDA in the US due to concerns about cardiovascular risks. Etoricoxib has been shown to be effective in reducing pain and swelling in joints and muscles, with clinical trials demonstrating a favorable safety profile when compared to Ibuprofen. Additionally, studies have suggested that Etoricoxib may be a more potent anti-inflammatory and analgesic drug compared to Ibuprofen, but it is being monitored for potential increased risk of myocardial infarction due to its COX-2 inhibition properties.
Aceclofenac is a nonsteroidal anti-inflammatory drug used to relieve pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is an analog of diclofenac and was patented in 1983 and approved for medical use in 1992. Aceclofenac works by inhibiting certain enzymes responsible for the formation of prostaglandin, which helps in relieving pain and reducing swelling. Long-term and high-dose usage of Aceclofenac can potentially cause kidney-related side effects. Aceclofenac is not the same as Ibuprofen or acetaminophen. It has marked anti-inflammatory and analgesic properties and has been demonstrated to be an effective and superior analgesic in the treatment of moderate to severe acute pain.