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Metamizole, also known as dipyrone, is a popular analgesic and anti-inflammatory drug used in human and veterinary medicine for pain relief, fever relief, and spasm relief. It is not approved for use in the United States. Metamizole is a pyrazolone derivative and belongs to the group of nonacid nonopioids. It is considered to be a potent analgesic, and is commonly used to treat pain (postoperative, colic, cancer, and migraine). However, it has been associated with life-threatening blood disorders and is banned in some countries. Metamizole is not the same as ibuprofen or paracetamol, although it has similar effects in relieving pain and fever. Metamizole is most commonly administered orally or through intravenous infusion.