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EGFR (estimated glomerular filtration rate) is a measure of how well the kidneys are working in filtering waste from the blood. The normal eGFR for adults is usually more than 90, but it declines with age even in people without kidney disease. A very low eGFR may indicate kidney failure. An eGFR test is used to evaluate kidney function, clinically. eGFR is an estimated number based on a blood test and age, sex, body type, and race. For patients younger than 40 years, CKD is defined by eGFR below 75 mL/min/1.73m2, for patients with ages between 40 and 65 years, CKD is defined by 60 mL/min/1.73m2. It is essential to know the cause of kidney disease and check the kidney function to plan treatment in case an eGFR falls below 60 for three months or more.