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Thiocolchicoside is a muscle relaxant with anti-inflammatory and analgesic effects, used in the treatment of orthopedic, traumatic, and rheumatologic disorders. Its mechanism of action is unclear, but it is believed to act via antagonism of nicotinic acetylcholine receptors, as well as GABAA and glycine receptors. It is safe for adolescents and adults, but caution should be exercised in patients with certain medical conditions. Its combination with Aceclofenac is used to reduce and relieve pain due to muscle spasms associated with various conditions. Thiocolchicoside has long been used as a muscle relaxant, despite a lack of proven efficacy beyond the placebo effect. There are some known side effects of thiocolchicoside, but it is generally considered safe when used as directed under the guidance of a healthcare professional.
